|
1 / 1
|
DeCS
|
|
 |
|
Descriptor English:
|
|
Mice, Inbred CFTR
|
|
Descriptor Spanish:
|
|
Ratones Consanguíneos CFTR
|
|
Descriptor Portuguese:
|
|
Camundongos Endogâmicos CFTR
|
|
Synonyms English:
|
|
Mice, CFTR
Mouse, CFTR
Mouse, Inbred CFTR
CFTR Mice
CFTR Mice, Inbred
CFTR Mouse
CFTR Mouse, Inbred
Inbred CFTR Mice
Inbred CFTR Mouse
|
|
Tree Number:
|
|
B01.050.050.199.520.520.445
B01.050.150.900.649.313.992.635.505.500.400.445
|
|
Definition English:
|
|
A strain of mice widely studied as a model for cystic fibrosis. These mice are generated from embryonic stem cells in which the CFTR (cystic fibrosis transmembrane conductance regulator) gene is inactivated by gene targeting. As a result, all mice have one copy of this altered gene in all their tissues. Mice homozygous for the disrupted gene exhibit many features common to young cystic fibrosis patients, including failure to thrive, meconium ileus, and alteration of mucous and serous glands. |
|
Indexing Annotation English:
|
|
NIM when exper animal: no qualif; when IM, qualif permitted; used a model for cystic fibrosis; do not forget also to check tag MICE
|
|
History Note English:
|
|
94
|
|
Allowable Qualifiers English:
|
|
|
|
Record Number:
|
|
31310
|
|
Unique Identifier:
|
|
D018181
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS CID-10 LILACS
|